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Did Cain have sex with his sister?

Cain lay with his wife, and she became pregnant and gave birth to Enoch. Cain was then building a city, and he named it after his son Enoch. Genesis 4:17

Yes. He had to. There was no one else around.

If everyone came from Adam and Eve and Cain was their son, then he had to have sex with Adam and Eve’s daughter, Cain’s sister.  The Bible does not mention Adam and Eve having any other children, but logically, where would she come from?  The only other option would be the daughter of Abel, his niece.  This would mean Abel had sex with his sister, also not mentioned.

While we may have a problem with that now, God didn’t at the time. Remember incest was not considered a sin until Leviticus 18, well into the time of Moses. 

The DNA of humans and the purity of their environment did not produce genetic problems until much later.

Also, it appeared that man’s intentions of sex became corrupted and men began to look at their sisters/daughters with impure thoughts. God put a stop to that.  

The only intention for Cain to have sex with his sister was procreation and the preservation of humanity.

There were no other humans created except the family line of Adam and Eve, so where else would they go to repopulate?